Anti-Aging·Intermediate·8 weeks

Cognitive — Nootropic Peptide Stack

Semax + Selank + Dihexa — focus, clarity, neuroprotection.

Overview

Three peptides with distinct mechanisms targeting cognition and neural function. Semax (BDNF modulator, focus/clarity), Selank (anxiolytic without sedation), and Dihexa (angiotensin IV analog, documented synaptogenesis effects in published studies). Intranasal administration is the common route for Semax and Selank — convenient and faster onset than subcutaneous. Dihexa is typically oral or topical.

Who it's for

  • 01Researchers investigating cognitive-performance protocols
  • 02Knowledge workers with focus / anxiety challenges
  • 03Researchers interested in neuroplasticity research

What's inside — 3 compounds

BDNF modulator — focus
Semax

5mg

Dose
0.3 mg
Frequency
2× daily
Weeks
1-8
Category
peptides

Intranasal — one drop per nostril AM + PM. Reconstitute with bacteriostatic saline.

Anxiolytic — calm focus
Selank

5mg

Dose
0.3 mg
Frequency
2× daily
Weeks
1-8
Category
peptides

Intranasal. Often stacked with Semax at the same administration time.

Neurogenesis — memory formation
Dihexa

10mg

Dose
15 mg
Frequency
Daily
Weeks
1-8
Category
peptides

Oral administration. Lipophilic — take with fat for absorption.

Weekly Protocol

All three run the full 8 weeks. Onset is fastest for Semax (days) and slowest for Dihexa (weeks). Intranasal reconstitution for Semax/Selank: bacteriostatic saline, small-volume spray bottle, refrigerated once mixed.

CompoundDoseFrequencyWeeks
Semax0.3 mg2× daily1-8
Selank0.3 mg2× daily1-8
Dihexa15 mgDaily1-8

Expected Outcomes

  • Measurable focus improvement within 3–7 days (Semax)
  • Reduced baseline anxiety (Selank)
  • Enhanced memory formation under learning load (Dihexa)
  • No hormonal effects, no PCT required

Safety & Warnings

  • Dihexa human data is limited — all human reports are anecdotal. Treat as investigational.
  • Intranasal reconstitution requires sterile technique and fresh BAC water.
  • Dihexa is lipophilic and potentially accumulates in brain tissue — no long-term data on extended use.

Frequently Asked

Will this make me smarter?

No nootropic 'makes you smarter.' These modulate attention, anxiety, and neural plasticity — you still have to do the work. But the feedback loop on learning, focused work, and sleep quality is often measurably improved.

Can I stack this with caffeine / nicotine?

Caffeine: yes, compatible. Nicotine: also compatible but separate mechanism. Stacking peptide nootropics with stimulants doesn't compound — they work on different axes.

Research disclaimer

All stack suggestions reflect the published literature and are provided for research-reference purposes only. Individual protocols require compound-specific planning. Consult the stacking theory guide before designing your protocol. Not medical advice.